Rejuran Hand vs Machine in Korea

24 December 2025

What Is Rejuran?

Rejuran is a skin rejuvenation treatment using polynucleotide (PN) injections to promote skin healing, regeneration, and elasticity. In Korea, Rejuran is widely used for improving texture, reducing fine lines, and strengthening skin quality.

Rejuran can be delivered by manual (hand) injection or by machine-assisted delivery (e.g., pneumatic or injector devices). The delivery method affects comfort, precision, and overall experience.

Rejuran Hand-Injected (Traditional Method)

Overview

Hand-injected Rejuran involves a dermatologist or injector placing small Rejuran doses directly into the dermis using a syringe and needle.

How It Works

  • Targeted microinjections placed by hand
  • Injected at specific depths based on skin needs
  • Precise placement controlled by clinician technique

Benefits

  • Precision control: The doctor can adjust depth and placement in real time
  • Customizable: Ideal for uneven areas or delicate zones (undereye, nasolabial, temples)
  • Clinician judgment: Experience guides optimal distribution

Considerations

  • Comfort: Some patients feel mild pinching
  • Technique dependent: Results vary with injector skill
  • Slower than machine: Manual delivery can take longer

Rejuran Machine-Assisted (Automatic or Pneumatic Injector)

Overview

Machine-assisted delivery uses an automatic injector or pneumatic device to deliver Rejuran into the skin. These devices can use pressure, multiple needles, or controlled depth settings.

How It Works

  • Device settings calibrate injection depth and speed
  • Multiple micro injections delivered uniformly
  • Often faster than manual technique

Benefits

  • More comfortable: Rapid micro doses reduce needle sensation
  • Consistent depth: Machine settings standardize delivery
  • Speed: Sessions can be quicker than manual injections

Considerations

  • Less flexible: Standard injection depths may be harder to customize
  • Device dependent: Results depend on technology quality
  • Less tactile feedback: Clinician has less direct control over each injection



Which Is Best for You?

Choose Hand-Injected If:

  • You have specific localized concerns (e.g., under eyes, scars)
  • You want clinician control over depth and placement
  • You prefer personalized injection adjustment

Choose Machine-Assisted If:

  • You prefer more comfort and speed
  • You want even coverage over large areas
  • You have sensitive skin or low pain tolerance

Comfort and Pain Management

Both methods can use topical numbing to reduce discomfort. Many clinics apply numbing cream before injection, and machine-assisted delivery may feel smoother due to rapid micro doses.

Expected Results

Whether delivered by hand or machine, Rejuran’s core benefits remain similar:

  • Improved elasticity and firmness
  • Smoother texture
  • Reduced fine lines
  • Stronger skin barrier function

Results continue to build over weeks as the polynucleotides support tissue regeneration.

Typical Session and Recovery

  • Duration: ~20–40 minutes
  • Downtime: Minimal; slight swelling or redness possible
  • Results: Gradual improvement over 2–4 weeks

Both techniques require similar aftercare.

Final Thoughts

Rejuran hand-injected and machine-assisted treatments both deliver regenerative skin benefits, but they differ in comfort, speed, and precision.

  • Hand injection offers high customization, ideal for targeted concerns.
  • Machine delivery offers greater comfort and faster sessions, suited for sensitive skin or larger treatment areas.


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